Saturday, August 7, 2010

overview of discovering structural variation with NGS

I think this presentation will be the last of three consecutive presentation in my firm.

so far, I have reviewed ChIP-seq, RNA-seq, de novo assembly (I didn't do posting of this subject, but I already made my own pipeline). I expect that after finishing this posting I can look over overall utilization of NGS, of course, I know this conclusion should be arrogant.

In my plan, these papers below will be introduced in presentation.

1. Computational methods for discovering structural variation with next-generation sequencing
2. one of the paper which is referred in paper 1.

I decide the second paper for presentation. that is beakDancer "BreakDancer: an algorithm for high-resolution mapping of genomic structural variation". haha Isn't it fascinated? Their sense for naming.. anyway It will come soon.