human epigenome project

As I try to study epigenomics, investigating global movement such as epigenome project to check available data is also important as much as studying biological investigation. And in that sense, I will introduce human epigenome project.

In 2003, scientists from UK's Sanger Institute and Epigenomics, Inc formed the Human Epigenome Project (http://science.howstuffworks.com/genetic-science/human-epigenome-project1.htm). According to website ( http://www.epigenome.org/index.php), The human epigenome project (HEP) is a collaboration run by the members in the Human Epigenome Consortium. One of the aims of the HEP is to generate tissue-specific DNA methylation reference profiles of the human genome. They use sodium bisulfite treatment, find MVPs (methylation variable positions) and release these data.

So far, two papers were published from here.

The first paper is "DNA methylation profiling of the human major histocompatibility complex: a pilot study for the human epigenome project" (http://www.ncbi.nlm.nih.gov/pubmed/15550986?dopt=Abstract)

and the second one is "DNA methylation profiling of human chromosomes 6, 20 and 22"

(http://www.ncbi.nlm.nih.gov/pubmed/17072317?dopt=Abstract).

releasing date from this is stopped in 2006. I am not sure whether their activities stopped.